Achromycin

Achromycin is a medicine

Main Indication

Tetracycline hydrochloride is indicated in infections caused by the following micro organisms: Rickettsiae (Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsial pox, tick fever). Mycoplasma pneumoniae (PPLO, Eaton agent). Agents of psittacosis. Agents of lymphogranuloma venereum and granuloma inguinale. The spirochaetal agent of relapsing fever (Borrelia recurrentis).

The following Gram-negative micro organism: Haemophilus ducreyi (chancroid), Pasteurella pestis and Pasteurella tularensis, Bartonella bacilliformis, Bacteroides species. Vibrio comma an Vibrio foetus. Brucella species (in conjection with streptomycin).

Tetracycline may be used for treatment of infections caused by the following Gram-negative micro organisms only when bacteriological testing indicates appropriate susceptibility to the drug: Escherichia coli, Enterobacter aerogenes (formerly Aerobacter aerogenes), Shigella species, Mima species and Herellea species, Haemophilus influenzae (respiratory infections), Klebsiella species (respiratory and urinary infections).

Tetracycline may be used for the treatment of infections caused by the following Gram- positive micro organisms when bacteriological testing indicates appropriate susceptibility to the drug: Streptococcus species: Up to 44% of strains of Streptococcus pyogenes and 74% of Streptococcus faecalis have been found to be resistant to tetracyclines. Therefore, tetracycline should not be used for streptococcal disease unless the organism has been demonstrated to be sensitive For upper respiratory infection due to group A ?-haemolytic streptococci (Streptococcus pyogenes), penicillin is the usual drug of choice, including prophylaxis of rheumatic fever. Streptococcus pneumoniae, Staphylococcus aureus in skin and soft tissue infections.

Tetracyclines are not the drug of choice in the treatment of any type of staphylococcal infection.

When penicillin is contraindicated, tetracyclines are alternative drugs in the treatment of infections due to: Treponema pallidum and Treponema pertenue (syphilis and yaws), Listeria monocytogenes, Clostridium species, Bacillus anthracis, Fusobacterium fusiforme (Vincent’s infection), Actinomyces species.

In acute intestinal amoebiasis, the tetracyclines may be a useful adjunct to amoebicides. In severe acne, the tetracyclines may be useful adjunctive therapy.

Tetracycline is indicated in the treatment of trachoma, although the infectious agent is not always eliminated, as judged by immunofluorescence.

Inclusion conjunctivitis may be treated with oral tetracyclines or with a combination of oral and topical agents.

Therapeutic Area

Antibiotics/Anti-Infectives

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Achromycin is available in these strengths:

• ACHROMYCIN tetracycline hydrochloride 250mg capsule blister pack