Zyloprim

Zyloprim is a Prescription medicine

Main Indication

Main clinical manifestation sofurate/uric acid deposition. These are gouty arthritis,skin tophi and/or renal involvement through crystal deposition or stone formation. Such clinical manifestations may occur in: idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate levels occur either spontaneously or after cytotoxic therapy, certain enzyme disorders which lead to overproduction of urate and involve:

• - hypoxanthine guanine phosphoribosyltransferase including Lesch-Nyhan syndrome,
• - lucose 6-phosphatase including glycogen storage disease,
• - phosphoribosylpyrophosphate synthetase,
• - phosphoribosylpyrophosphate amidotransferase.

ZYLOPRIM is indicated for the management of 2,8-dihydroxyadenine (2,8-DHA) renal stones related to deficient activity of adenine phosphoribosyl transferase.
ZYLOPRIM is indicated for the management of recurrent mixed calcium oxalate renal stones in the presence of hyperuricosuria, when fluid, dietary and similar measures have failed.

Therapeutic Area

Metabolism

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Zyloprim is available in these strengths:

• Zyloprim 100mg Tablets
• Zyloprim 300mg Tablets