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Main Indication:

Treatment of mild to moderately severe infections caused by penicillin sensitive staphylococci, pneumococci, gonococci and haemolytic streptococci infections. Therapy should be guided by bacteriological studies, including sensitivity tests, and by clinical response.

For prophylactic use in recurrent streptococcal infections including the prevention of recurrence following rheumatic fever and/or Sydenham’s chorea and to prevent bacterial endocarditis in patients with rheumatic fever and/or congenital heart disease who are about to undergo dental or upper respiratory surgery or instrumentation.

Note: Oral penicillin should not be used as adjunctive prophylaxis for genitourinary instrumentation or surgery, lower intestinal tract surgery, sigmoidoscopy or childbirth.

Main Indication:

Treatment of mild to moderately severe infections caused by penicillin sensitive staphylococci, pneumococci, gonococci and haemolytic streptococci infections. Therapy should be guided by bacteriological studies, including sensitivity tests, and by clinical response.

For prophylactic use in recurrent streptococcal infections including the prevention of recurrence following rheumatic fever and/or Sydenham’s chorea and to prevent bacterial endocarditis in patients with rheumatic fever and/or congenital heart disease who are about to undergo dental or upper respiratory surgery or instrumentation.

Note: Oral penicillin should not be used as adjunctive prophylaxis for genitourinary instrumentation or surgery, lower intestinal tract surgery, sigmoidoscopy or childbirth.

Main Indication:

Abelcet is indicated for the treatment of invasive fungal disease caused by organisms susceptible to amphotericin B

Main Indication:

Pain

Main Indication:

Aclor is indicated for the treatment of the following types of infections caused by or likely to be caused by susceptible organisms:

• Lower respiratory infections, including pneumonia, bronchitis and exacerbations of chronic bronchitis.
• Upper respiratory infections, including pharyngitis, tonsillitis and otitis media. Skin and skin structure infections.
• Urinary tract infections, including pyelonephritis and cystitis.

Main Indication:

Treatment of type 2 diabetes mellitus inadequately controlled by diet and exercise:

• as monotherapy;
• as dual therapy to improve glycaemic control
• - in combination with metformin or sulfonylurea
• - in combination with insulin;
• as triple therapy to improve glycaemic control, in combination with metformin and sulfonylurea.

Main Indication:

Treatment of hypertension. It may be used alone or in combination with thiazide diuretics. Sufficient data have not been provided to support the use of quinapril in renovascular hypertension.

Congestive heart failure. Adjunctive treatment of mild to moderate congestive heart failure when given concomitantly with a diuretic and/or cardiac glycoside.

Main Indication:

Relief of unproductive, dry and intractable coughs associated with colds and flu.

Main Indication:

Actiq is indicated for the management of breakthrough cancer pain in patients with malignancies who are already receiving and are tolerant to opioid therapy for their underlying persistent cancer pain.

Main Indication:

Treatment of hypertension. Prophylaxis of chronic stable angina pectoris.

Main Indication:

Moderate asthmatic attacks; chronic forms of asthma; asthma in patients with diminished cardiac reserve; chronic obstructive bronchitis with bronchospasm; bronchospasm during or after surgery, use during assisted ventilation with a respirator.

Main Indication:

AGGRASTAT, in combination with heparin, is indicated for patients with unstable angina or non-Q-wave myocardial infarction to prevent cardiac ischaemic events.

Main Indication:

Hypertension (mild, moderate to severe).

Main Indication:

Treatment of osteoporosis, including glucocorticoid induced osteoporosis. Osteoporosis must be confirmed by the finding of low bone mass of at least two standard deviations below the gender specific mean for young adults, or by the presence of osteoporotic fracture. Paget's disease of bone.

Main Indication:

Treatment of patients with multiple myeloma for whom oral therapy is not appropriate.

Main Indication:

Palliative treatment of multiple myeloma and advanced ovarian adenocarcinoma.

Main Indication:

Treatment of major depression

Main Indication:

Main clinical manifestations of urate/uric acid deposition. These are gouty arthritis, skin tophi and/or renal involvement through crystal deposition or stone formation. Such clinical manifestations may occur in: idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate levels occur either spontaneously or after cytotoxic therapy, certain enzyme disorders which lead to overproduction of urate and involve:

• • hypoxanthine guanine phosphoribosyltransferase including Lesch-Nyhan syndrome,
• • glucose 6-phosphatase including glycogen storage disease,
• • phosphoribosylpyrophosphate synthetase,
• • phosphoribosylpyrophosphate amidotransferase.

Management of 2,8-dihydroxyadenine (2,8-DHA) renal stones related to deficient activity of adenine phosphoribosyl transferase.

Management of recurrent mixed calcium oxalate renal stones in the presence of hyperuricosuria, when fluid, dietary and similar measures have failed.

Main Indication:

Anxiety: the short-term symptomatic treatment of anxiety including treatment of anxious patients with some symptoms of depression; Panic Disorder: the treatment of panic disorder with or without some phobic avoidance, and for blocking or attenuation of panic attacks and phobias in patients who have agoraphobia with panic attacks.

Main Indication:

Anxiety: the short-term symptomatic treatment of anxiety including treatment of anxious patients with some symptoms of depression; Panic Disorder: the treatment of panic disorder with or without some phobic avoidance, and for blocking or attenuation of panic attacks and phobias in patients who have agoraphobia with panic attacks.

Main Indication:

Treatment of acute and chronic schizophrenic disorders, in which positive symptoms (such as delusions, hallucinations, thought disorders) and/or negative symptoms (such as blunted affect, emotional and social withdrawal) are prominent.

Main Indication:

Hypertension. First line treatment of mild to moderate essential hypertension. It can be used as the sole agent to control blood pressure in the majority of patients. Patients not adequately controlled on a single antihypertensive agent may benefit from the addition of amlodipine, which has been used in combination with a thiazide diuretic, beta-adrenoreceptor blocking agent, or an angiotensin converting enzyme inhibitor.

Angina. First line treatment of chronic stable angina. Amlodipine may be used alone, as monotherapy, or in combination with other antianginal drugs.

Main Indication:

AMOXIL is used to treat a range of infections caused by bacteria. These may be infections of the chest (pneumonia), tonsils (tonsillitis), sinuses (sinusitis), urinary and genital tract, skin and fleshy tissues. AMOXIL works by killing the bacteria that cause these infections. AMOXIL can also be used to prevent infection.

Main Indication:

AMOXIL is used to treat a range of infections caused by bacteria. These may be infections of the chest (pneumonia), tonsils (tonsillitis), sinuses (sinusitis), urinary and genital tract, skin and fleshy tissues. AMOXIL works by killing the bacteria that cause these infections. AMOXIL can also be used to prevent infection.

Main Indication:

Amoxycillin belongs to the penicillin group of antibiotics. AMOXIL is used to treat a range of infections caused by bacteria. These may be infections of the blood (septicaemia), chest (pneumonia), urinary and genital tract, skin and fleshy tissues.

Main Indication:

Treatment of infections due to susceptible strains of Gram-positive and Gram-negative organisms

Main Indication:

• • Major depression.
• • Obsessive-compulsive disorders and phobias in adults.
• • Cataplexy associated with narcolepsy.

Main Indication:

For the symptomatic relief of headache, nausea and vomiting associated with migraine.

Main Indication:

Main Indication:

Relief of severe pain (medical and surgical) where non-narcotic analgesics and other measures do not provide satisfactory relief. Except in patients with terminal conditions, use of Anamorph should be restricted to short-term administration.

Main Indication:

Early breast cancer Adjuvant treatment of early breast cancer in postmenopausal women with oestrogen/progesterone-receptor-positive disease. Advanced breast cancer First line treatment of advanced breast cancer in postmenopausal women with oestrogen/progesterone-receptor-positive disease.

Main Indication:

ANDEPRA is indicated for the treatment of major depressive disorder (MDD). ANDEPRA is indicated for the treatment of diabetic peripheral neuropathic pain (DPNP). ANDEPRA is indicated for the treatment of generalised anxiety disorder (GAD).

Main Indication:

For the relief of heartburn and indigestion

Main Indication:

Treatment of acute angina pectoris.

As well as relieving pain of an acute attack, it may be used prophylactically before physical exertion or mental stress which would be expected to produce an anginal attack.

Main Indication:

Main Indication:

ANTABUSE Tablets are indicated to act as a deterrent to alcohol consumption and an aid in the overall management of selected chronic alcoholic patients involved in an integrated programme of counselling and psychiatry. Only alcoholic patients who are motivated to abstain from drinking and who are undergoing supportive psychotherapeutic treatment, ancillary to a total programme of rehabilitation, should be selected for ANTABUSE administration.

Main Indication:

• Orally for treatment of cryptococcal meningitis in patients who are unable to tolerate amphotericin B. Note. Data suggest that the clinical efficacy of fluconazole is lower than that of amphotericin B in the treatment of the acute phase of cryptococcal meningitis. • Maintenance therapy to prevent relapse of cryptococcal meningitis in patients with acquired immune deficiency syndrome (AIDS). • Treatment of oropharyngeal and oesophageal candidiasis in AIDS and other immunosuppressed patients. • Secondary prophylaxis of oropharyngeal candidiasis in patients with human immunodeficiency virus (HIV) infection. • Serious and life-threatening Candida infections in patients who are unable to tolerate amphotericin B. Note. It remains to be shown that fluconazole is as effective as amphotericin B in the treatment of serious and life-threatening Candida infections. Until such data are available, amphotericin B remains the drug of choice. • Vaginal candidiasis, when topical therapy has failed. • Treatment of extensive tinea corporis, extensive tinea cruris and extensive tinea pedis infections in immunocompetent patients in whom topical therapy is not a practical treatment option. Usually, topical therapy should be attempted first because oral therapy has a less favourable ratio of benefits to risks

Main Indication:

To be used as an adjunct to diet, exercise and weight loss, in lowering blood glucose in patients with non-insulin dependent (Type 2) diabetes mellitus.

Main Indication:

Indicated for moderate asthmatic attacks; chronic forms of asthma; asthma in patients with diminished cardiac reserve; chronic obstructive bronchitis with bronchospasm; bronchospasm during or after surgery, use during assisted ventilation with a respirator.

Main Indication:

Treatment of hypertension. Prophylaxis of chronic stable angina pectoris

Main Indication:

Ondansetron is indicated for the prevention and treatment of nausea and vomiting induced by cytotoxic therapy and radiotherapy.

Main Indication:

Apo-Paracetamol/Codeine 500/30 is indicated for the relief of moderate to severe pain which does not respond to milder analgesics.

Main Indication:

Treatment of primary restless legs syndrome, including the reduction of associated periodic limb movement and episodes of nocturnal arousal.

Main Indication:

Donepezil hydrochloride is indicated for the treatment of mild, moderate and severe Alzheimer's disease.

Main Indication:

Treatment of the following dermatoses: atopic dermatitis, eczematous dermatitis, nummular eczema, contact dermatitis, anal and vulval pruritus, otitis externa, seborrhoeic dermatitis, eczematised psoriasis, neurodermatitis.

Main Indication:

AROPAX is indicated for the treatment of: major depression and for the prevention of relapse of depressive symptoms; Obsessive Compulsive Disorder and for the prevention of relapse of OCD; Panic Disorder and for the prevention of relapse of Panic Disorder; Social Anxiety Disorder/Social Phobia; Generalised Anxiety Disorder; and Post-traumatic Stress Disorder

Main Indication:

As an adjunct in the therapy of all forms of Parkinsonism (postencephalitis, arteriosclerotic and idiopathic). It is useful in the prevention or control of extrapyramidal disorders due to CNS drugs such as phenothiazines.

Main Indication:

Treatment of scabies and body pediculosis.

Main Indication:

For the temporary relief of pain and discomfort associated with migraine headache, earache, period pain, rheumatic pain. Reduces fever and inflammation.

Main Indication:

For the rapid conversion to a normal sinus rhythm of paroxysmal supraventricular tachycardias, including those associated with accessory bypass tracts (Wolff-Parkinson-White syndrome).

Main Indication:

Adrenaline 1:10,000. An adjunct in the management of cardiac arrest. Adrenaline 1:1,000. The drug of choice in the emergency treatment of acute severe anaphylactic reactions due to insect bites, drugs and other allergens. It may also be used for the symptomatic relief of respiratory distress due to bronchospasm.

Main Indication:

Main Indication:

Main Indication:

Hospitalised adult patients in whom oral ciprofloxacin is indicated but cannot be administered or where the oral form is inappropriate. For the treatment of serious or life threatening infections due to sensitive organisms involving the following organ systems:

• - Lower respiratory tract infections (gram-negative organisms)
• - Skin and skin structure
• - Septicaemia
• - Bone and joint - Urinary tract

Inhalational anthrax (post-exposure): To reduce the incidence or progression of disease following exposure to aerosolized Bacillus anthracis. Ciprofloxacin serum concentrations achieved in humans serve as a surrogate endpoint reasonably likely to predict clinical benefit and provide the basis for this indication.

Main Indication:

Short duration analgesia during premedication, induction and maintenance of anaesthesia, and in the immediate postoperative period.

Opioid analgesic supplement to general and regional anaesthesia.

Combination with a neuroleptic as an anaesthetic premedication for the induction of anaesthesia, and as an adjunct in the maintenance of general and regional anaesthesia.

Main Indication:

Indicated for the following conditions but should be used only when fluconazole cannot be administered orally:

• • Treatment of cryptococcal meningitis in patients who are unable to tolerate amphotericin B. Note: Data suggest that the clinical efficacy of fluconazole is lower than that of amphotericin B in the treatment of the acute phase of cryptococcal meningitis.
• • Maintenance therapy to prevent relapse of cryptococcal meningitis in patients with acquired immune deficiency syndrome (AIDS).
• • Treatment of oropharyngeal and oesophageal candidiasis in AIDS and other immunosuppressed patients.
• • Secondary prophylaxis of oropharyngeal candidiasis in patients with human immunodeficiency virus (HIV) infection.
• • Serious and life threatening Candida infections in patients who are unable to tolerate amphotericin B. Note: It remains to be shown that fluconazole is as effective as amphotericin B in the treatment of serious and life threatening Candida infections. Until such data are available, amphotericin B remains the drug of choice.

Main Indication:

Treatment of major depression, obsessive compulsive disorder (OCD) and premenstrual dysphoric disorder (PMDD) as defined by DSM-IV criteria.

Main Indication:

Management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic. The physician should periodically reassess the usefulness of the drug for the individual patient. Pre-surgical medication taken the night before surgery and/or 1-2 hours prior to the surgical procedure.

Main Indication:

Indicated where it is necessary to dilate the pupil and paralyse accommodation.

Main Indication:

AUGMENTIN DUO 400 oral suspension is indicated in the short term treatment of the following bacterial infections when caused by sensitive organisms: Skin and Skin Structure Infections; Urinary Tract Infections (complicated and uncomplicated); Upper Respiratory Tract Infections including sinusitis and otitis media; Lower Respiratory Tract Infections including acute exacerbations of chronic bronchitis and community acquired pneumonia

Main Indication:

AUGMENTIN TABLETS are indicated for short term treatment of bacterial infections at the following sites when caused by sensitive organisms (refer to Microbiology): Urinary Tract Infections (uncomplicated and complicated) Lower Respiratory Tract Infections, including community acquired pneumonia and acute exacerbations of chronic bronchitis; Upper Respiratory Tract Infections, such as sinusitis, otitis media and recurrent tonsillitis; Skin and Skin Structure Infection

Main Indication:

AUGMENTIN SYRUP is used to treat a wide range of infections caused by bacteria. These infections may affect the chest (e.g. bronchitis or pneumonia), bladder (e.g. cystitis), sinuses (e.g. sinusitis), the ears (e.g. otitis media) or the skin.

Main Indication:

Major depression.

Obsessive Compulsive Disorder.

Premenstrual Dysphoric Disorder (PMDD) as defined by DSM-IV criteria.

Main Indication:

• • Duodenal ulcer
• • Benign gastric ulcer
• • Zollinger-Ellison syndrome
• • Prevention of relapses of duodenal ulceration.
• • Short-term (no more than 12 weeks) symptomatic relief of gastroesophageal reflux not responsive to conservative measures.
• • Healing of oesophageal erosion or ulceration associated with gastroesophageal reflux disease.
• • Prevention of relapses of symptoms and erosions or ulcerations associated with gastroesophageal reflux disease.

Main Indication:

• • Hypertension: All grades of essential hypertension Renovascular hypertension
• • Congestive Heart Failure: All degrees of symptomatic heart failure. In such patients, it is recommended that AUSPRIL be administered together with a diuretic.
• • Left Ventricular Dysfunction: All degrees of left ventricular dysfunction where the left ventricular ejection fraction is less than 35%, irrespective of the presence or severity of obvious symptoms of heart failure.

Main Indication:

Short-term treatment of proven duodenal ulcer and gastric ulcer.

Maintenance treatment to reduce the risk of relapse in duodenal ulcer.

Maintenance treatment for periods up to one year to reduce the risk of relapse in patients with documented healing of benign gastric ulcer.

Treatment of gastrinoma (Zollinger-Ellison syndrome).

Short-term symptomatic treatment of reflux oesophagitis unresponsive to conservative antireflux measures and simple drug therapies such as antacids.

Maintenance treatment to reduce the risk of relapse of reflux oesophagitis. Treatment of scleroderma oesophagitis.

Main Indication:

Treatment of infections due to susceptible strains of Gram-positive and Gram-negative organisms. Bacteriological studies to determine the organism and its sensitivity should be undertaken.

Main Indication:

Azathioprine is used as an immunosuppressant / antimetabolite either alone or, more commonly, in combination with the other agents (usually corticosteroids) and procedures which influence the immune response. Therapeutic effects may be evident only after weeks or months and can include a steroid-sparing effect, thereby reducing the toxicity associated with high dosage and prolonged usage of corticosteroids.

Azathioprine, in combination with corticosteroids and / or other immunosuppressive agents and procedures, is indicated in the management of patients receiving organ transplants.

Azathioprine, either alone or more usually in combination with corticosteroids and/or other procedures, has been used with clinical benefit which may include reduction of dosage or discontinuation of corticosteroids, in a proportion of patients suffering from the following: severe rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis/polymyositis, autoimmune chronic active hepatitis, pemphigus vulgaris, polyarteritis nodosa, autoimmune haemolytic anaemia, and chronic refractory idiopathic thrombocytopenic purpura.

Main Indication:

Community acquired pneumonia caused by susceptible organisms in patients who require initial intravenous therapy. In clinical studies efficacy has been demonstrated against Chlamydia pneumoniae, Haemophilus influenzae, Legionella pneumophilia,Moraxella catarrhalis, Mycoplasma pneumoniae, Staphylococcus aureus and Streptococcus pneumoniae.